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+4: Target player exiles a card from their hand.
−3: Exile target permanent.
−14: Restart the game, leaving in exile all non-Aura permanent cards exiled with Karn. Then put those cards onto the battlefield under your control.
Read from the rules text. A card that enables a keyword makes or is the thing; a card that rewards it gets better when you have it. Two cards interact when one enables what the other rewards.
